What is the 4th wire?...you just have to wire four wires to a 0.1 inch connector.
Possibly but that makes it far more complicated. You can't use HSPI commands, you can't have the same capabilities of background receive, and the code I have ( admittedly including debugging capabilities ) is nearly 4000 bytes long and uses 38 byte variables. You may do better at using less resources but would likely have to start compromising on software to make it fit and it would be much harder to code and debug.Maybe it can do also with some extra memory chip too? With 18M2 chip?