Make sure the AXE027cable is connected and select Device Manager.
On Windows 10 right-click on the "My Computer" icon, select Properties, then follow the Device Manager link at the top left.
Do not use the Settings app or Control Panel / Devices and Printers as they may look a bit like Device Manager but are not, and don't so easily allow what needs to be done.
Select the AXE027 devices (probably those with yellow exclamation marks alongside them if none explicitly identified as AXE027), and click Update drivers.
Point Device Manager to the directory containing the drivers. The top level directory must be selected; the one containing the 'amd64' and 'i386' sub-directories.
Note that the installation is a two-step process as two drivers must be installed. If the second step is not completed then there will be issues in accessing the installed AXE027 cable. After installing the first driver look for any new exclamation marked devices.